glycosylated hemoglobin การใช้

• Glycosylated hemoglobin is the form of hemoglobin to which glucose is bound.
• Poor control of T2DM results in high levels of glycosylated hemoglobin in the red blood cells.
• This test, the hemoglobin A1c or glycosylated hemoglobin reflects average glucoses over the preceding 2 3 months.
• The test has different versions and names : glycosylated hemoglobin, glycated hemoglobin, hemoglobin A1c or just A1c.
• In support of the association, finasteride improves glucose metabolism and decreases glycosylated hemoglobin HbA1c, a surrogate marker for diabetes mellitus.
• While the technology has its limitations, studies have demonstrated that patients with continuous sensors experience less hyperglycemia and also reduce their glycosylated hemoglobin levels.
• An author of the study, Dr . Sherita Hill Golden, said it suggested that any one percentage point lowering of glycosylated hemoglobin would help people with diabetes.
• In nondiabetic persons with normal glucose metabolism the glycosylated hemoglobin is usually 4-6 % by the most common methods ( normal ranges may vary by method ).
• :Re question 2 . our article on Glycosylated hemoglobin gives some history about the discovery of HbA1c . talk 03 : 16, 23 January 2008 ( UTC)
• Other diagnostic tests to determine the level of diabetic control are fructosamine and glycosylated hemoglobin ( GHb ) blood tests which can be useful especially if stress may be a factor.
• Diabetics who keep their glycosylated hemoglobin levels close to 7 % have a much better chance of avoiding the complications that may accompany diabetes ( than those whose levels are 8 % or higher ).
• Shantha GP, Kumar AA, Kahan S, Cheskin LJ . Association between glycosylated hemoglobin and intentional weight loss in overweight and obese patients with type 2 diabetes mellitus : a retrospective cohort study.
• Researchers found significant positive correlations between NAS consumption and various metabolic syndromes, such as increased weight and waist-to-hip ratio, higher fasting blood glucose, glycosylated hemoglobin and measures of impaired tolerance.
• Though difficult to obtain, values less than 7 % are recommended for people with T2DM . Levels greater than 9 % are associated with poor control of the glycosylated hemoglobin, and levels greater than 12 % are associated with very poor control.
• In Type 2 diabetes, for every one percentage-point increase in glycosylated hemoglobin, there was an 18 percent increase in the risk for heart disease or stroke, and a 28 percent increase in the risk for artery disease in the legs.
• For example, the results of a 2008 study propose that older women with higher levels of environmental mastery, positive relations with others, and self-acceptance showed lower levels of glycosylated hemoglobin, which is a marker for glucose levels / insulin resistance.
• Poor glycemic control refers to persistently elevated blood glucose and glycosylated hemoglobin levels, which may range from 200 500 mg / dl ( 11-28 mmol / L ) and 9-15 % or higher over months and years before severe complications occur.
• However, despite this revolution, the use of SMBG and electronic reports, although fully supported by the American Diabetes Association, never reached its potential due in part to the popularization of glycosylated hemoglobin ( HbA1c ) as the primary basis for clinical decision-making.
• However, the binding to hemoglobin does serve as a record for average blood glucose levels over the lifetime of red cells, which is approximately 120 days . The levels of glycosylated hemoglobin are therefore measured in order to monitor the long-term control of the chronic disease of type 2 diabetes mellitus ( T2DM ).
• In a clinical study that compared the efficacy and safety of using Levemir for the treatment of patients with type 2 diabetes who had suboptimal glycemic control while receiving maximally tolerated doses of metformin and sulfonylurea ( common tablet therapies for type 2 diabetes ), it was found that, " At 24 weeks, HbA 1c ( glycosylated hemoglobin ) had decreased by 1.8 and 1.9 % ( from 8.6 to 6.8 and from 8.5 to 6.6 % ) for detemir and NPH, respectively ( NS ).